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AT-7519

Synonyms

SourcesNames Used
GDSC1000AT-7519
PharmacoGx AT-7519

External IDs

DatabaseIdentifier
Smiles: Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem: 11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

FDA Approval Status

Not Approved
Dataset Select
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Top molecular features associated with response to AT-7519


Feature TypeStandardized
Nominal ANOVA
mRNA SPATA5L1 GDSC1000 pan-cancer AAC 0.11 0.0002
mRNA ERCC1 GDSC1000 pan-cancer AAC -0.11 0.0002
mRNA ZNF516 GDSC1000 pan-cancer AAC 0.11 0.0002
mRNA TMEM144 GDSC1000 pan-cancer AAC -0.12 0.0002
mRNA ABCC1 GDSC1000 pan-cancer AAC -0.11 0.0002
mRNA EDEM2 GDSC1000 pan-cancer AAC -0.11 0.0002
mRNA GNA15 GDSC1000 pan-cancer AAC 0.13 0.0002
mRNA BMP4 GDSC1000 pan-cancer AAC -0.13 0.0002
mRNA ZNF136 GDSC1000 pan-cancer AAC 0.12 0.0002
mRNA NCKAP1L GDSC1000 pan-cancer AAC 0.18 0.0002
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