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AT-7519

Synonyms

SourcesNames Used
GDSC1000AT-7519
PharmacoGx AT-7519

External IDs

DatabaseIdentifier
Smiles: Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem: 11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

FDA Approval Status

Not Approved
Dataset Select
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Top molecular features associated with response to AT-7519


Feature TypeStandardized
Nominal ANOVA
mRNA TRAM2 GDSC1000 pan-cancer AAC -0.13 9e-05
mRNA ETV3L GDSC1000 pan-cancer AAC -0.11 9e-05
mRNA MVP GDSC1000 pan-cancer AAC -0.13 0.0001
mRNA ITGA2B GDSC1000 pan-cancer AAC -0.11 0.0001
mRNA TJP1 GDSC1000 pan-cancer AAC -0.22 0.0001
mRNA PROSER1 GDSC1000 pan-cancer AAC 0.13 0.0001
mRNA ZBTB6 GDSC1000 pan-cancer AAC 0.12 0.0001
mRNA SEMA3C GDSC1000 pan-cancer AAC -0.13 0.0001
mRNA ADGRF4 GDSC1000 pan-cancer AAC 0.12 0.0001
mRNA TAB2 GDSC1000 pan-cancer AAC 0.12 0.0001
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