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AT-7519

Synonyms

SourcesNames Used
GDSC1000AT-7519
PharmacoGx AT-7519

External IDs

DatabaseIdentifier
Smiles: Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem: 11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

FDA Approval Status

Not Approved
Dataset Select
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Top molecular features associated with response to AT-7519


Feature TypeStandardized
Nominal ANOVA
mRNA YTHDC1 GDSC1000 pan-cancer AAC 0.17 5e-08
mRNA NCBP3 GDSC1000 pan-cancer AAC 0.16 6e-08
mRNA GPAT3 GDSC1000 pan-cancer AAC -0.17 8e-08
mRNA NDFIP1 GDSC1000 pan-cancer AAC -0.16 1e-07
mRNA NRF1 GDSC1000 pan-cancer AAC 0.17 1e-07
mRNA PPIC GDSC1000 pan-cancer AAC -0.21 1e-07
mRNA PNN GDSC1000 pan-cancer AAC 0.18 1e-07
mRNA TSPAN4 GDSC1000 pan-cancer AAC -0.19 1e-07
mRNA IKZF1 GDSC1000 pan-cancer AAC 0.38 1e-07
mRNA MGAT4B GDSC1000 pan-cancer AAC -0.18 1e-07
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