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AT-7519

Synonyms

SourcesNames Used
GDSC1000AT-7519
PharmacoGx AT-7519

External IDs

DatabaseIdentifier
Smiles: Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem: 11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

FDA Approval Status

Not Approved
Dataset Select
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Top molecular features associated with response to AT-7519


Feature TypeStandardized
Nominal ANOVA
mRNA EHF GDSC1000 pan-cancer AAC 0.14 6e-05
mRNA PLRG1 GDSC1000 pan-cancer AAC 0.12 6e-05
mRNA TRA2A GDSC1000 pan-cancer AAC 0.12 6e-05
mRNA ZNF133 GDSC1000 pan-cancer AAC 0.12 6e-05
mRNA UPF3B GDSC1000 pan-cancer AAC 0.13 6e-05
mRNA RPS27L GDSC1000 pan-cancer AAC -0.13 6e-05
mRNA RALB GDSC1000 pan-cancer AAC -0.12 6e-05
mRNA DEF6 GDSC1000 pan-cancer AAC 0.17 6e-05
mRNA KDF1 GDSC1000 pan-cancer AAC 0.16 6e-05
mRNA MED30 GDSC1000 pan-cancer AAC 0.13 6e-05
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