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AT-7519

Synonyms

SourcesNames Used
GDSC1000AT-7519
PharmacoGx AT-7519

External IDs

DatabaseIdentifier
Smiles: Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem: 11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

FDA Approval Status

Not Approved
Dataset Select
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Top molecular features associated with response to AT-7519


Feature TypeStandardized
Nominal ANOVA
mRNA CHD2 GDSC1000 pan-cancer AAC 0.13 2e-05
mRNA RMI1 GDSC1000 pan-cancer AAC 0.13 2e-05
mRNA ITGB5 GDSC1000 pan-cancer AAC -0.16 2e-05
mRNA CCDC66 GDSC1000 pan-cancer AAC 0.14 2e-05
mRNA NNMT GDSC1000 pan-cancer AAC -0.15 2e-05
mRNA RBM25 GDSC1000 pan-cancer AAC 0.13 2e-05
mRNA ARPC1B GDSC1000 pan-cancer AAC -0.14 2e-05
mRNA BCL11A GDSC1000 pan-cancer AAC 0.14 2e-05
mRNA THAP9 GDSC1000 pan-cancer AAC 0.13 2e-05
mRNA MSL2 GDSC1000 pan-cancer AAC 0.15 2e-05
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