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AT-7519

Synonyms

SourcesNames Used
GDSC1000AT-7519
PharmacoGx AT-7519

External IDs

DatabaseIdentifier
Smiles: Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem: 11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

FDA Approval Status

Not Approved
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Top molecular features associated with response to AT-7519


Feature TypeStandardized
Nominal ANOVA
mRNA EBF2 GDSC1000 pan-cancer AAC 0.081 0.005
mRNA CRIP3 GDSC1000 pan-cancer AAC 0.084 0.005
mRNA ASPHD1 GDSC1000 pan-cancer AAC -0.095 0.005
mRNA FLAD1 GDSC1000 pan-cancer AAC 0.087 0.005
mRNA KIAA1429 GDSC1000 pan-cancer AAC 0.084 0.005
mRNA CHD3 GDSC1000 pan-cancer AAC 0.086 0.005
mRNA PEA15 GDSC1000 pan-cancer AAC -0.097 0.005
mRNA MORN4 GDSC1000 pan-cancer AAC -0.091 0.005
mRNA ERCC2 GDSC1000 pan-cancer AAC -0.081 0.005
mRNA EBF3 GDSC1000 pan-cancer AAC 0.087 0.005
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