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AT-7519

Synonyms

SourcesNames Used
GDSC1000AT-7519
PharmacoGx AT-7519

External IDs

DatabaseIdentifier
Smiles: Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem: 11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

FDA Approval Status

Not Approved
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Top molecular features associated with response to AT-7519


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF195 GDSC1000 pan-cancer AAC 0.15 6e-06
mRNA THOC2 GDSC1000 pan-cancer AAC 0.14 6e-06
mRNA TNFRSF12A GDSC1000 pan-cancer AAC -0.19 6e-06
mRNA STXBP6 GDSC1000 pan-cancer AAC -0.14 6e-06
mRNA RRP7A GDSC1000 pan-cancer AAC 0.13 6e-06
mRNA DIS3 GDSC1000 pan-cancer AAC 0.14 6e-06
mRNA AGO4 GDSC1000 pan-cancer AAC 0.14 7e-06
mRNA DRAM1 GDSC1000 pan-cancer AAC -0.15 7e-06
mRNA CNOT6 GDSC1000 pan-cancer AAC 0.14 7e-06
mRNA EDNRB GDSC1000 pan-cancer AAC -0.18 7e-06
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