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AT-7519

Synonyms

SourcesNames Used
GDSC1000AT-7519
PharmacoGx AT-7519

External IDs

DatabaseIdentifier
Smiles: Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem: 11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

FDA Approval Status

Not Approved
Dataset Select
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Top molecular features associated with response to AT-7519


Feature TypeStandardized
Nominal ANOVA
mRNA MYCBP2 GDSC1000 pan-cancer AAC 0.18 9e-07
mRNA CEP295 GDSC1000 pan-cancer AAC 0.15 1e-06
mRNA FHL2 GDSC1000 pan-cancer AAC -0.18 1e-06
mRNA FGF2 GDSC1000 pan-cancer AAC -0.16 1e-06
mRNA PDE7A GDSC1000 pan-cancer AAC 0.17 1e-06
mRNA TXNRD1 GDSC1000 pan-cancer AAC -0.16 1e-06
mRNA SECISBP2 GDSC1000 pan-cancer AAC 0.15 1e-06
mRNA SPR GDSC1000 pan-cancer AAC -0.19 1e-06
mRNA PPP4R3A GDSC1000 pan-cancer AAC 0.16 1e-06
mRNA STOM GDSC1000 pan-cancer AAC -0.15 1e-06
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