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AT-7519

Synonyms

SourcesNames Used
GDSC1000AT-7519
PharmacoGx AT-7519

External IDs

DatabaseIdentifier
Smiles: Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem: 11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

FDA Approval Status

Not Approved
Dataset Select
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Top molecular features associated with response to AT-7519


Feature TypeStandardized
Nominal ANOVA
mRNA ABCB1 GDSC1000 pan-cancer AAC -0.29 6e-19
mRNA PRPF4B GDSC1000 pan-cancer AAC 0.22 7e-13
mRNA CCAR1 GDSC1000 pan-cancer AAC 0.22 2e-11
mRNA ZNF232 GDSC1000 pan-cancer AAC 0.19 5e-11
mRNA DUSP3 GDSC1000 pan-cancer AAC -0.21 1e-10
mRNA MDFI GDSC1000 pan-cancer AAC 0.2 2e-10
mRNA CREB1 GDSC1000 pan-cancer AAC 0.2 3e-10
mRNA CTSA GDSC1000 pan-cancer AAC -0.21 6e-10
mRNA CD63 GDSC1000 pan-cancer AAC -0.22 1e-09
mRNA SNRNP48 GDSC1000 pan-cancer AAC 0.19 2e-09
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