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AT-7519

Synonyms

SourcesNames Used
GDSC1000AT-7519
PharmacoGx AT-7519

External IDs

DatabaseIdentifier
Smiles: Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem: 11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

FDA Approval Status

Not Approved
Dataset Select
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Top molecular features associated with response to AT-7519


Feature TypeStandardized
Nominal ANOVA
mRNA GNG12 GDSC1000 pan-cancer AAC -0.25 6e-09
mRNA SQSTM1 GDSC1000 pan-cancer AAC -0.19 8e-09
mRNA SHISA4 GDSC1000 pan-cancer AAC -0.21 9e-09
mRNA CPQ GDSC1000 pan-cancer AAC -0.19 9e-09
mRNA SLC47A1 GDSC1000 pan-cancer AAC -0.17 9e-09
mRNA ZNF292 GDSC1000 pan-cancer AAC 0.18 9e-09
mRNA EPDR1 GDSC1000 pan-cancer AAC -0.19 1e-08
mRNA TTF1 GDSC1000 pan-cancer AAC 0.17 1e-08
mRNA DICER1 GDSC1000 pan-cancer AAC 0.17 1e-08
mRNA CRTAP GDSC1000 pan-cancer AAC -0.19 1e-08
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