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AT-7519

Synonyms

SourcesNames Used
GDSC1000AT-7519
PharmacoGx AT-7519

External IDs

DatabaseIdentifier
Smiles: Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem: 11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

FDA Approval Status

Not Approved
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Top molecular features associated with response to AT-7519


Feature TypeStandardized
Nominal ANOVA
mRNA ARHGEF28 GDSC1000 pan-cancer AAC -0.1 0.004
mRNA BRD3 GDSC1000 pan-cancer AAC 0.088 0.004
mRNA ASS1 GDSC1000 pan-cancer AAC 0.094 0.004
mRNA DHRS13 GDSC1000 pan-cancer AAC 0.088 0.004
mRNA ROPN1 GDSC1000 pan-cancer AAC -0.11 0.004
mRNA DDOST GDSC1000 pan-cancer AAC -0.086 0.004
mRNA FSTL3 GDSC1000 pan-cancer AAC -0.094 0.004
mRNA RALGAPA1 GDSC1000 pan-cancer AAC 0.087 0.004
mRNA TMEM234 GDSC1000 pan-cancer AAC -0.086 0.004
mRNA ATG4C GDSC1000 pan-cancer AAC 0.095 0.004
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