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AT-7519

Synonyms

SourcesNames Used
GDSC1000AT-7519
PharmacoGx AT-7519

External IDs

DatabaseIdentifier
Smiles: Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem: 11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

FDA Approval Status

Not Approved
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Top molecular features associated with response to AT-7519


Feature TypeStandardized
Nominal ANOVA
mRNA CWF19L2 GDSC1000 pan-cancer AAC 0.15 8e-07
mRNA WDR33 GDSC1000 pan-cancer AAC 0.17 8e-07
mRNA SRSF11 GDSC1000 pan-cancer AAC 0.15 8e-07
mRNA CASZ1 GDSC1000 pan-cancer AAC 0.16 8e-07
mRNA CHTOP GDSC1000 pan-cancer AAC 0.15 8e-07
mRNA C20orf196 GDSC1000 pan-cancer AAC 0.17 9e-07
mRNA LRMP GDSC1000 pan-cancer AAC 0.23 9e-07
mRNA KIFC3 GDSC1000 pan-cancer AAC -0.17 9e-07
mRNA SBK1 GDSC1000 pan-cancer AAC 0.17 9e-07
mRNA TRA2B GDSC1000 pan-cancer AAC 0.16 9e-07
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