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AT-7519

Synonyms

SourcesNames Used
GDSC1000AT-7519
PharmacoGx AT-7519

External IDs

DatabaseIdentifier
Smiles: Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem: 11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

FDA Approval Status

Not Approved
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Top molecular features associated with response to AT-7519


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF787 GDSC1000 pan-cancer AAC -0.084 0.005
mRNA APOF GDSC1000 pan-cancer AAC -0.081 0.005
mRNA SYCE2 GDSC1000 pan-cancer AAC 0.083 0.005
mRNA GON4L GDSC1000 pan-cancer AAC 0.088 0.005
mRNA WWOX GDSC1000 pan-cancer AAC 0.087 0.005
mRNA E2F8 GDSC1000 pan-cancer AAC 0.092 0.005
mRNA SWT1 GDSC1000 pan-cancer AAC 0.085 0.005
mRNA DPYSL5 GDSC1000 pan-cancer AAC 0.095 0.005
mRNA SCRIB GDSC1000 pan-cancer AAC 0.086 0.005
mRNA AIM1 GDSC1000 pan-cancer AAC 0.09 0.005
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