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AT-7519

Synonyms

SourcesNames Used
GDSC1000AT-7519
PharmacoGx AT-7519

External IDs

DatabaseIdentifier
Smiles: Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem: 11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

FDA Approval Status

Not Approved
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Top molecular features associated with response to AT-7519


Feature TypeStandardized
Nominal ANOVA
mRNA NIPBL GDSC1000 pan-cancer AAC 0.12 5e-05
mRNA PANK2 GDSC1000 pan-cancer AAC 0.12 5e-05
mRNA FERMT2 GDSC1000 pan-cancer AAC -0.16 5e-05
mRNA TKT GDSC1000 pan-cancer AAC -0.12 5e-05
mRNA HSPG2 GDSC1000 pan-cancer AAC -0.13 5e-05
mRNA TNS3 GDSC1000 pan-cancer AAC -0.12 5e-05
mRNA ZNF430 GDSC1000 pan-cancer AAC 0.13 5e-05
mRNA RPUSD2 GDSC1000 pan-cancer AAC 0.13 5e-05
mRNA C11orf68 GDSC1000 pan-cancer AAC -0.12 5e-05
mRNA SMIM8 GDSC1000 pan-cancer AAC 0.13 5e-05
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