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AT-7519

Synonyms

SourcesNames Used
GDSC1000AT-7519
PharmacoGx AT-7519

External IDs

DatabaseIdentifier
Smiles: Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem: 11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

FDA Approval Status

Not Approved
Dataset Select
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Top molecular features associated with response to AT-7519


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF146 GDSC1000 pan-cancer AAC 0.12 3e-05
mRNA C20orf96 GDSC1000 pan-cancer AAC 0.13 3e-05
mRNA FZD3 GDSC1000 pan-cancer AAC 0.13 3e-05
mRNA LAMC1 GDSC1000 pan-cancer AAC -0.16 3e-05
mRNA MCPH1 GDSC1000 pan-cancer AAC 0.13 3e-05
mRNA LTBR GDSC1000 pan-cancer AAC -0.15 4e-05
mRNA DLL1 GDSC1000 pan-cancer AAC 0.13 4e-05
mRNA VSTM1 GDSC1000 pan-cancer AAC -0.12 4e-05
mRNA ASL GDSC1000 pan-cancer AAC -0.12 4e-05
mRNA TP53 GDSC1000 pan-cancer AAC 0.12 4e-05
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