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AT-7519

Synonyms

SourcesNames Used
GDSC1000AT-7519
PharmacoGx AT-7519

External IDs

DatabaseIdentifier
Smiles: Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem: 11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

FDA Approval Status

Not Approved
Dataset Select
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Top molecular features associated with response to AT-7519


Feature TypeStandardized
Nominal ANOVA
mRNA PKP1 GDSC1000 pan-cancer AAC 0.15 1e-05
mRNA ZNF117 GDSC1000 pan-cancer AAC 0.13 1e-05
mRNA FAM114A1 GDSC1000 pan-cancer AAC -0.16 1e-05
mRNA CYB5R3 GDSC1000 pan-cancer AAC -0.15 1e-05
mRNA YTHDF2 GDSC1000 pan-cancer AAC 0.13 1e-05
mRNA RCC2 GDSC1000 pan-cancer AAC 0.15 1e-05
mRNA BCKDK GDSC1000 pan-cancer AAC -0.13 1e-05
mRNA GJB6 GDSC1000 pan-cancer AAC 0.14 1e-05
mRNA NUDT16 GDSC1000 pan-cancer AAC -0.13 1e-05
mRNA HNRNPDL GDSC1000 pan-cancer AAC 0.14 1e-05
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