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AT-7519

Synonyms

SourcesNames Used
GDSC1000AT-7519
PharmacoGx AT-7519

External IDs

DatabaseIdentifier
Smiles: Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem: 11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

FDA Approval Status

Not Approved
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Top molecular features associated with response to AT-7519


Feature TypeStandardized
Nominal ANOVA
mRNA RIOK1 GDSC1000 pan-cancer AAC 0.14 4e-06
mRNA SDPR GDSC1000 pan-cancer AAC -0.14 4e-06
mRNA TNFRSF14 GDSC1000 pan-cancer AAC -0.17 4e-06
mRNA PTGR1 GDSC1000 pan-cancer AAC -0.18 4e-06
mRNA ARID2 GDSC1000 pan-cancer AAC 0.15 4e-06
mRNA GMEB1 GDSC1000 pan-cancer AAC 0.15 5e-06
mRNA SHPRH GDSC1000 pan-cancer AAC 0.15 5e-06
mRNA GBP6 GDSC1000 pan-cancer AAC 0.16 5e-06
mRNA ZNF398 GDSC1000 pan-cancer AAC 0.14 5e-06
mRNA BUD13 GDSC1000 pan-cancer AAC 0.14 5e-06
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