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AT-7519

AT-7519

Synonyms

Sources	Names Used
GDSC1000	AT-7519
PharmacoGx	AT-7519

External IDs

Database	Identifier
Smiles:	Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem:	11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AT-7519

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	STAG2	GDSC1000	pan-cancer	AAC	0.082	0.005
mRNA	TANC2	GDSC1000	pan-cancer	AAC	0.094	0.005
mRNA	S100A9	GDSC1000	pan-cancer	AAC	0.089	0.005
mRNA	FRMD6	GDSC1000	pan-cancer	AAC	-0.099	0.005
mRNA	RHOV	GDSC1000	pan-cancer	AAC	0.095	0.005
mRNA	TMEM70	GDSC1000	pan-cancer	AAC	0.085	0.005
mRNA	C6orf47	GDSC1000	pan-cancer	AAC	0.082	0.005
mRNA	STX2	GDSC1000	pan-cancer	AAC	-0.094	0.005
mRNA	CCNT2	GDSC1000	pan-cancer	AAC	0.082	0.005
mRNA	PDE7B	GDSC1000	pan-cancer	AAC	-0.082	0.005

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