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Y-39983

Y-39983

Synonyms

Sources	Names Used
GDSC1000	Y-39983
PharmacoGx	Y-39983

External IDs

Database	Identifier
Smiles:	C[C@@H](N)c1ccc(cc1)C(=O)Nc1ccnc2[nH]ccc12
Pubchem:	9810884

Annotated Targets

ROCK1, ROCK2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to Y-39983

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZNF763	GDSC1000	pan-cancer	AAC	0.09	0.007
mRNA	ZNF75A	GDSC1000	pan-cancer	AAC	0.078	0.02
mRNA	ZNF749	GDSC1000	pan-cancer	AAC	0.078	0.02
mRNA	ZNF71	GDSC1000	pan-cancer	AAC	0.09	0.01
mRNA	ZNF699	GDSC1000	pan-cancer	AAC	0.073	0.02
mRNA	ZNF682	GDSC1000	pan-cancer	AAC	0.089	0.008
mRNA	ZNF675	GDSC1000	pan-cancer	AAC	0.087	0.01
mRNA	ZNF674	GDSC1000	pan-cancer	AAC	0.088	0.007
mRNA	ZNF665	GDSC1000	pan-cancer	AAC	0.09	0.006
mRNA	ZNF654	GDSC1000	pan-cancer	AAC	0.13	0.0004

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