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Y-39983

Y-39983

Synonyms

Sources	Names Used
GDSC1000	Y-39983
PharmacoGx	Y-39983

External IDs

Database	Identifier
Smiles:	C[C@@H](N)c1ccc(cc1)C(=O)Nc1ccnc2[nH]ccc12
Pubchem:	9810884

Annotated Targets

ROCK1, ROCK2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to Y-39983

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	TIMM21	GDSC1000	pan-cancer	AAC	0.077	0.02
mRNA	DEPDC5	GDSC1000	pan-cancer	AAC	0.086	0.02
mRNA	KIAA0319L	GDSC1000	pan-cancer	AAC	-0.074	0.02
mRNA	SLC24A5	GDSC1000	pan-cancer	AAC	-0.094	0.02
mRNA	MRPL52	GDSC1000	pan-cancer	AAC	-0.074	0.02
mRNA	SLC29A2	GDSC1000	pan-cancer	AAC	-0.08	0.02
mRNA	ASAH1	GDSC1000	pan-cancer	AAC	-0.077	0.02
mRNA	GLMP	GDSC1000	pan-cancer	AAC	-0.082	0.02
mRNA	SLC37A4	GDSC1000	pan-cancer	AAC	-0.076	0.02
mRNA	DHCR7	GDSC1000	pan-cancer	AAC	-0.074	0.02

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