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Y-39983

Y-39983

Synonyms

Sources	Names Used
GDSC1000	Y-39983
PharmacoGx	Y-39983

External IDs

Database	Identifier
Smiles:	C[C@@H](N)c1ccc(cc1)C(=O)Nc1ccnc2[nH]ccc12
Pubchem:	9810884

Annotated Targets

ROCK1, ROCK2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to Y-39983

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PCNT	GDSC1000	pan-cancer	AAC	0.084	0.02
mRNA	TRIM23	GDSC1000	pan-cancer	AAC	0.078	0.02
mRNA	ZSCAN29	GDSC1000	pan-cancer	AAC	0.084	0.02
mRNA	HIST1H2AD	GDSC1000	pan-cancer	AAC	-0.077	0.02
mRNA	ATRAID	GDSC1000	pan-cancer	AAC	-0.077	0.02
mRNA	PHLDA2	GDSC1000	pan-cancer	AAC	-0.089	0.02
mRNA	FBXW5	GDSC1000	pan-cancer	AAC	-0.077	0.02
mRNA	WDR62	GDSC1000	pan-cancer	AAC	0.081	0.02
mRNA	EXTL2	GDSC1000	pan-cancer	AAC	0.084	0.02
mRNA	SLFN12L	GDSC1000	pan-cancer	AAC	0.078	0.02

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