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Y-39983

Y-39983

Synonyms

Sources	Names Used
GDSC1000	Y-39983
PharmacoGx	Y-39983

External IDs

Database	Identifier
Smiles:	C[C@@H](N)c1ccc(cc1)C(=O)Nc1ccnc2[nH]ccc12
Pubchem:	9810884

Annotated Targets

ROCK1, ROCK2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to Y-39983

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MDM1	GDSC1000	pan-cancer	AAC	0.081	0.02
mRNA	FAM219A	GDSC1000	pan-cancer	AAC	-0.078	0.02
mRNA	HAT1	GDSC1000	pan-cancer	AAC	0.078	0.02
mRNA	TRIM33	GDSC1000	pan-cancer	AAC	0.079	0.02
mRNA	SMC4	GDSC1000	pan-cancer	AAC	0.079	0.02
mRNA	RNF213	GDSC1000	pan-cancer	AAC	-0.077	0.02
mRNA	LMOD1	GDSC1000	pan-cancer	AAC	0.076	0.02
mRNA	THUMPD3	GDSC1000	pan-cancer	AAC	0.077	0.02
mRNA	CEP63	GDSC1000	pan-cancer	AAC	0.08	0.02
mRNA	RPA1	GDSC1000	pan-cancer	AAC	0.077	0.02

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