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Y-39983

Y-39983

Synonyms

Sources	Names Used
GDSC1000	Y-39983
PharmacoGx	Y-39983

External IDs

Database	Identifier
Smiles:	C[C@@H](N)c1ccc(cc1)C(=O)Nc1ccnc2[nH]ccc12
Pubchem:	9810884

Annotated Targets

ROCK1, ROCK2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to Y-39983

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MRPL10	GDSC1000	pan-cancer	AAC	-0.08	0.02
mRNA	ORMDL2	GDSC1000	pan-cancer	AAC	-0.08	0.02
mRNA	TMEM182	GDSC1000	pan-cancer	AAC	-0.078	0.02
mRNA	ZNF749	GDSC1000	pan-cancer	AAC	0.078	0.02
mRNA	LYPD6B	GDSC1000	pan-cancer	AAC	-0.082	0.02
mRNA	ARHGEF1	GDSC1000	pan-cancer	AAC	-0.09	0.02
mRNA	SLC35A1	GDSC1000	pan-cancer	AAC	0.079	0.02
mRNA	MASTL	GDSC1000	pan-cancer	AAC	0.078	0.02
mRNA	FAM92A1	GDSC1000	pan-cancer	AAC	0.085	0.02
mRNA	MARCH7	GDSC1000	pan-cancer	AAC	0.078	0.02

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