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XL-184

XL-184

Synonyms

Sources	Names Used
GDSC1000	XL-184
PharmacoGx	XL-184

External IDs

Database	Identifier
Pubchem:	25102847

Annotated Targets

MET, KDR, KIT, TEK

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to XL-184

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PRSS57	GDSC1000	pan-cancer	AAC	0.38	2e-26
mRNA	FLT3	GDSC1000	pan-cancer	AAC	0.35	2e-24
mRNA	TIFAB	GDSC1000	pan-cancer	AAC	0.32	1e-22
mRNA	PPP1R27	GDSC1000	pan-cancer	AAC	0.31	1e-21
mRNA	OCSTAMP	GDSC1000	pan-cancer	AAC	0.31	1e-20
mRNA	MS4A6A	GDSC1000	pan-cancer	AAC	0.31	6e-20
mRNA	CD300LF	GDSC1000	pan-cancer	AAC	0.28	7e-16
mRNA	CCR2	GDSC1000	pan-cancer	AAC	0.27	6e-15
mRNA	CCL23	GDSC1000	pan-cancer	AAC	0.26	2e-14
mRNA	CSF1R	GDSC1000	pan-cancer	AAC	0.26	2e-14

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