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XL-184

XL-184

Synonyms

Sources	Names Used
GDSC1000	XL-184
PharmacoGx	XL-184

External IDs

Database	Identifier
Pubchem:	25102847

Annotated Targets

MET, KDR, KIT, TEK

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to XL-184

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	KCNN3	GDSC1000	pan-cancer	AAC	-0.14	0.0002
mRNA	PPM1F	GDSC1000	pan-cancer	AAC	0.13	0.0002
mRNA	ITGAM	GDSC1000	pan-cancer	AAC	0.13	0.0002
mRNA	ARRDC2	GDSC1000	pan-cancer	AAC	0.14	0.0002
mRNA	SUN2	GDSC1000	pan-cancer	AAC	0.13	0.0002
mRNA	CXCR2	GDSC1000	pan-cancer	AAC	0.13	0.0002
mRNA	ST8SIA6	GDSC1000	pan-cancer	AAC	0.12	0.0002
mRNA	GFI1	GDSC1000	pan-cancer	AAC	0.16	0.0002
mRNA	GNA15	GDSC1000	pan-cancer	AAC	0.15	0.0002
mRNA	SIGLEC5	GDSC1000	pan-cancer	AAC	0.13	0.0002

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