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XL-184

XL-184

Synonyms

Sources	Names Used
GDSC1000	XL-184
PharmacoGx	XL-184

External IDs

Database	Identifier
Pubchem:	25102847

Annotated Targets

MET, KDR, KIT, TEK

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to XL-184

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	TCF7L2	GDSC1000	pan-cancer	AAC	0.15	0.0001
mRNA	SNX20	GDSC1000	pan-cancer	AAC	0.16	0.0001
mRNA	CD101	GDSC1000	pan-cancer	AAC	0.13	0.0001
mRNA	IKZF3	GDSC1000	pan-cancer	AAC	-0.15	0.0001
mRNA	ZMIZ1	GDSC1000	pan-cancer	AAC	0.14	0.0001
mRNA	INPP5D	GDSC1000	pan-cancer	AAC	0.2	0.0001
mRNA	TRIM26	GDSC1000	pan-cancer	AAC	-0.14	0.0001
mRNA	PPM1H	GDSC1000	pan-cancer	AAC	-0.14	0.0001
mRNA	SOWAHD	GDSC1000	pan-cancer	AAC	0.14	0.0001
mRNA	CFAP161	GDSC1000	pan-cancer	AAC	0.13	0.0001

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