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semagacestat

semagacestat

Synonyms

Sources	Names Used
CTRPv2	semagacestat
PharmacoGx	semagacestat

External IDs

Database	Identifier
Pubchem:	9843750

Annotated Targets

PSEN1, APH1A, NCSTN, PSENEN

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to semagacestat

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	APOBR	CTRPv2	pan-cancer	AAC	-0.092	0.02
mRNA	ISLR2	CTRPv2	pan-cancer	AAC	0.095	0.02
mRNA	HLA-DPB1	CTRPv2	pan-cancer	AAC	0.093	0.02
mRNA	ZNF429	CTRPv2	pan-cancer	AAC	0.09	0.02
mRNA	OTUD6B	CTRPv2	pan-cancer	AAC	-0.085	0.02
mRNA	MRPL37	CTRPv2	pan-cancer	AAC	-0.085	0.02
mRNA	POLR2H	CTRPv2	pan-cancer	AAC	-0.086	0.02
mRNA	C2orf42	CTRPv2	pan-cancer	AAC	0.091	0.02
mRNA	LRRC2	CTRPv2	pan-cancer	AAC	0.086	0.02
mRNA	GPKOW	CTRPv2	pan-cancer	AAC	-0.085	0.02

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