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semagacestat

semagacestat

Synonyms

Sources	Names Used
CTRPv2	semagacestat
PharmacoGx	semagacestat

External IDs

Database	Identifier
Pubchem:	9843750

Annotated Targets

PSEN1, APH1A, NCSTN, PSENEN

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to semagacestat

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PRM2	CTRPv2	pan-cancer	AAC	0.085	0.02
mRNA	MARCH11	CTRPv2	pan-cancer	AAC	0.1	0.02
mRNA	EPHA10	CTRPv2	pan-cancer	AAC	0.095	0.02
mRNA	NCK2	CTRPv2	pan-cancer	AAC	0.097	0.02
mRNA	LCTL	CTRPv2	pan-cancer	AAC	0.095	0.02
mRNA	MNAT1	CTRPv2	pan-cancer	AAC	-0.092	0.02
mRNA	FCGR2A	CTRPv2	pan-cancer	AAC	-0.089	0.02
mRNA	GPR61	CTRPv2	pan-cancer	AAC	0.086	0.02
mRNA	MTERF3	CTRPv2	pan-cancer	AAC	-0.085	0.02
mRNA	CD1B	CTRPv2	pan-cancer	AAC	0.084	0.02

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