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semagacestat

semagacestat

Synonyms

Sources	Names Used
CTRPv2	semagacestat
PharmacoGx	semagacestat

External IDs

Database	Identifier
Pubchem:	9843750

Annotated Targets

PSEN1, APH1A, NCSTN, PSENEN

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to semagacestat

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	APC2	CTRPv2	pan-cancer	AAC	0.11	0.02
mRNA	REL	CTRPv2	pan-cancer	AAC	0.088	0.02
mRNA	SPTBN1	CTRPv2	pan-cancer	AAC	0.1	0.02
mRNA	DHX33	CTRPv2	pan-cancer	AAC	-0.089	0.02
mRNA	KMT2C	CTRPv2	pan-cancer	AAC	0.091	0.02
mRNA	ZHX1-C8orf76	CTRPv2	pan-cancer	AAC	-0.088	0.02
mRNA	CDH17	CTRPv2	pan-cancer	AAC	0.096	0.02
mRNA	BRD4	CTRPv2	pan-cancer	AAC	0.089	0.02
mRNA	RAG1	CTRPv2	pan-cancer	AAC	0.087	0.02
mRNA	CD3G	CTRPv2	pan-cancer	AAC	0.087	0.02

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