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clofarabine

clofarabine

Synonyms

Sources	Names Used
CTRPv2	clofarabine
PharmacoGx	clofarabine

External IDs

Database	Identifier
Smiles:	Nc1nc(Cl)nc2n(cnc12)C3OC(CO)C(O)C3F
Inchikey:	WDDPHFBMKLOVOX-UHFFFAOYSA-N
Pubchem:	119182

Annotated Targets

POLA1, POLD1, POLE, RRM1, RRM2, RRM2B

FDA Approval Status

Approved

Dataset Select

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Top molecular features associated with response to clofarabine

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	RPL4	CTRPv2	pan-cancer	AAC	0.12	0.0002
mRNA	TES	CTRPv2	pan-cancer	AAC	-0.11	0.0002
mRNA	SLAMF7	CTRPv2	pan-cancer	AAC	-0.11	0.0003
mRNA	CENPVL1	CTRPv2	pan-cancer	AAC	0.12	0.0003
mRNA	SLC25A40	CTRPv2	pan-cancer	AAC	0.11	0.0003
mRNA	PA2G4	CTRPv2	pan-cancer	AAC	0.11	0.0003
mRNA	SSBP3	CTRPv2	pan-cancer	AAC	0.11	0.0003
mRNA	CHTF18	CTRPv2	pan-cancer	AAC	0.11	0.0003
mRNA	RASGRP2	CTRPv2	pan-cancer	AAC	0.13	0.0003
mRNA	RAG1	CTRPv2	pan-cancer	AAC	0.11	0.0003

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