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AC220

AC220

Synonyms

Sources	Names Used
GDSC1000	AC220
PharmacoGx	AC220

External IDs

Database	Identifier
Pubchem:	24889392

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AC220

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	LST1	GDSC1000	pan-cancer	AAC	0.35	1e-17
mRNA	TYROBP	GDSC1000	pan-cancer	AAC	0.34	2e-22
mRNA	MYB	GDSC1000	pan-cancer	AAC	0.34	8e-12
mRNA	RAB37	GDSC1000	pan-cancer	AAC	0.34	5e-18
mRNA	FAM78A	GDSC1000	pan-cancer	AAC	0.33	2e-12
mRNA	PRTN3	GDSC1000	pan-cancer	AAC	0.33	5e-22
mRNA	SIGLEC7	GDSC1000	pan-cancer	AAC	0.32	2e-21
mRNA	ATP8B4	GDSC1000	pan-cancer	AAC	0.32	6e-19
mRNA	CYSLTR1	GDSC1000	pan-cancer	AAC	0.31	2e-15
mRNA	P2RX1	GDSC1000	pan-cancer	AAC	0.31	6e-15

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