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AC220

AC220

Synonyms

Sources	Names Used
GDSC1000	AC220
PharmacoGx	AC220

External IDs

Database	Identifier
Pubchem:	24889392

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AC220

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	FGL2	GDSC1000	pan-cancer	AAC	0.2	2e-09
mRNA	POU2AF1	GDSC1000	pan-cancer	AAC	-0.27	2e-09
mRNA	PLCB2	GDSC1000	pan-cancer	AAC	0.23	2e-09
mRNA	SYNGR1	GDSC1000	pan-cancer	AAC	0.22	2e-09
mRNA	TMEM243	GDSC1000	pan-cancer	AAC	-0.21	2e-09
mRNA	PARVG	GDSC1000	pan-cancer	AAC	0.25	3e-09
mRNA	TSKS	GDSC1000	pan-cancer	AAC	0.2	4e-09
mRNA	VENTX	GDSC1000	pan-cancer	AAC	0.22	4e-09
mRNA	LYL1	GDSC1000	pan-cancer	AAC	0.28	4e-09
mRNA	CACNA2D4	GDSC1000	pan-cancer	AAC	0.21	5e-09

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