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OSI-930

OSI-930

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	OSI-930
PharmacoGx	OSI-930

External IDs

Database	Identifier
Smiles:	FC(F)(F)Oc1ccc(NC(=O)c2sccc2NCc2ccnc3ccccc23)cc1
Pubchem:	9868037

Annotated Targets

KIT, KDR, FLT1

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to OSI-930

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	NCSTN	CTRPv2	pan-cancer	AAC	-0.11	0.004
mRNA	KCNIP2	CTRPv2	pan-cancer	AAC	0.1	0.004
mRNA	ZNF669	CTRPv2	pan-cancer	AAC	0.11	0.004
mRNA	PTS	GDSC1000	pan-cancer	AAC	-0.11	0.004
mRNA	FBLL1	CTRPv2	pan-cancer	AAC	0.14	0.004
mRNA	ARHGAP33	CTRPv2	pan-cancer	AAC	0.11	0.004
mRNA	TPTE2	CTRPv2	pan-cancer	AAC	0.11	0.004
mRNA	TCP10L	CTRPv2	pan-cancer	AAC	0.11	0.004
mRNA	HTR1E	CTRPv2	pan-cancer	AAC	0.13	0.004
mRNA	GPR162	GDSC1000	pan-cancer	AAC	0.11	0.004

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