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ifosfamide

Synonyms

SourcesNames Used
CTRPv2ifosfamide
PharmacoGx ifosfamide

External IDs

DatabaseIdentifier
Smiles: ClCCN[P@]1(=O)OCCCN1CCCl
Inchikey: HOMGKSMUEGBAAB-UHFFFAOYSA-N
Pubchem: 3690

Annotated Targets

CYP2A6, CYP2B6, CYP2C18, CYP2C19, CYP2C8, CYP2C9, CYP3A4, CYP3A5, CYP3A7, PTGS1

FDA Approval Status

Approved
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Top molecular features associated with response to ifosfamide


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF425 CTRPv2 pan-cancer AAC 0.15 0.005
mRNA ADAMTS9 CTRPv2 pan-cancer AAC 0.16 0.005
mRNA FAM122B CTRPv2 pan-cancer AAC -0.15 0.005
mRNA LRP1 CTRPv2 pan-cancer AAC 0.18 0.005
mRNA REPS1 CTRPv2 pan-cancer AAC -0.15 0.005
mRNA CCDC13 CTRPv2 pan-cancer AAC 0.15 0.005
mRNA CLGN CTRPv2 pan-cancer AAC -0.15 0.005
mRNA RUFY4 CTRPv2 pan-cancer AAC 0.14 0.006
mRNA GIT1 CTRPv2 pan-cancer AAC -0.15 0.006
mRNA PODXL2 CTRPv2 pan-cancer AAC -0.16 0.006
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