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ABT-737

Synonyms

SourcesNames Used
CTRPv2ABT-737
PharmacoGx ABT-737

External IDs

DatabaseIdentifier
Smiles: CN(C)CCC(CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC(=O)C3=CC=C(C=C3)N4CCN(CC4)CC5=CC=CC=C5C6=CC=C(C=C6)Cl)[N+](=O)[O-]
Inchikey: HPLNQCPCUACXLM-PGUFJCEWSA-N
Pubchem: 11228183

Annotated Targets

BCL2, BCL2L1, BCL2L2

FDA Approval Status

Not Approved
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Top molecular features associated with response to ABT-737


Feature TypeStandardized
Nominal ANOVA
mRNA DOPEY1 CTRPv2 pan-cancer AAC 0.25 7e-12
mRNA SBK1 CTRPv2 pan-cancer AAC 0.26 1e-11
mRNA BCL11A CTRPv2 pan-cancer AAC 0.28 1e-11
mRNA ZNF43 CTRPv2 pan-cancer AAC 0.26 2e-11
mRNA TMSB15A CTRPv2 pan-cancer AAC 0.26 2e-11
mRNA BSN CTRPv2 pan-cancer AAC 0.27 2e-11
mRNA FXYD6 CTRPv2 pan-cancer AAC 0.25 2e-11
mRNA RP3-403A15.5 CTRPv2 pan-cancer AAC 0.28 3e-11
mRNA BAHCC1 CTRPv2 pan-cancer AAC 0.24 3e-11
mRNA STXBP5L CTRPv2 pan-cancer AAC 0.24 3e-11
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