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ABT-737

Synonyms

SourcesNames Used
CTRPv2ABT-737
PharmacoGx ABT-737

External IDs

DatabaseIdentifier
Smiles: CN(C)CCC(CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC(=O)C3=CC=C(C=C3)N4CCN(CC4)CC5=CC=CC=C5C6=CC=C(C=C6)Cl)[N+](=O)[O-]
Inchikey: HPLNQCPCUACXLM-PGUFJCEWSA-N
Pubchem: 11228183

Annotated Targets

BCL2, BCL2L1, BCL2L2

FDA Approval Status

Not Approved
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Top molecular features associated with response to ABT-737


Feature TypeStandardized
Nominal ANOVA
mRNA NAPB CTRPv2 pan-cancer AAC 0.25 3e-12
mRNA PARP15 CTRPv2 pan-cancer AAC 0.27 3e-12
mRNA KIAA0408 CTRPv2 pan-cancer AAC 0.29 3e-12
mRNA ZNF260 CTRPv2 pan-cancer AAC 0.27 3e-12
mRNA TP73 CTRPv2 pan-cancer AAC 0.25 4e-12
mRNA DNMT3A CTRPv2 pan-cancer AAC 0.27 5e-12
mRNA FBXO25 CTRPv2 pan-cancer AAC 0.25 6e-12
mRNA BEND5 CTRPv2 pan-cancer AAC 0.25 6e-12
mRNA CBFA2T2 CTRPv2 pan-cancer AAC 0.25 7e-12
mRNA GPC2 CTRPv2 pan-cancer AAC 0.3 7e-12
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