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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA CDKN2D GDSC1000 pan-cancer AAC -0.12 0.0009
mRNA MAPK3 GDSC1000 pan-cancer AAC -0.11 0.0009
mRNA CAMK2N2 GDSC1000 pan-cancer AAC -0.11 0.001
mRNA SEPT7 GDSC1000 pan-cancer AAC 0.12 0.001
mRNA NUP62CL GDSC1000 pan-cancer AAC 0.13 0.001
mRNA INSR GDSC1000 pan-cancer AAC -0.12 0.001
mRNA C4orf3 GDSC1000 pan-cancer AAC -0.11 0.001
mRNA TMEM121 GDSC1000 pan-cancer AAC -0.11 0.001
mRNA TGM2 GDSC1000 pan-cancer AAC 0.12 0.001
mRNA RRAGD GDSC1000 pan-cancer AAC -0.12 0.001
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