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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA PRSS23 GDSC1000 pan-cancer AAC 0.12 0.009
mRNA PMEPA1 GDSC1000 pan-cancer AAC 0.1 0.009
mRNA SNRK GDSC1000 pan-cancer AAC -0.1 0.009
mRNA ERBIN GDSC1000 pan-cancer AAC 0.091 0.009
mRNA CXCL6 GDSC1000 pan-cancer AAC 0.09 0.009
mRNA C19orf54 GDSC1000 pan-cancer AAC -0.094 0.009
mRNA USP25 GDSC1000 pan-cancer AAC 0.091 0.009
mRNA G2E3 GDSC1000 pan-cancer AAC 0.091 0.009
mRNA PICALM GDSC1000 pan-cancer AAC 0.091 0.009
mRNA SIGLEC10 GDSC1000 pan-cancer AAC 0.098 0.009
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