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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA FAM210B GDSC1000 pan-cancer AAC -0.12 0.008
mRNA FAM109B GDSC1000 pan-cancer AAC 0.091 0.008
mRNA LRRN2 GDSC1000 pan-cancer AAC -0.093 0.008
mRNA TNFAIP1 GDSC1000 pan-cancer AAC 0.12 0.008
mRNA TRIP11 GDSC1000 pan-cancer AAC 0.093 0.008
mRNA CLIP2 GDSC1000 pan-cancer AAC -0.093 0.008
mRNA BBX GDSC1000 pan-cancer AAC 0.089 0.009
mRNA LAMB3 GDSC1000 pan-cancer AAC 0.11 0.009
mRNA MXI1 GDSC1000 pan-cancer AAC -0.094 0.009
mRNA CHD3 GDSC1000 pan-cancer AAC 0.094 0.009
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