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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA SEMA3C GDSC1000 pan-cancer AAC 0.1 0.007
mRNA FAM135B GDSC1000 pan-cancer AAC -0.092 0.008
mRNA DNAH1 GDSC1000 pan-cancer AAC -0.1 0.008
mRNA DDX6 GDSC1000 pan-cancer AAC -0.094 0.008
mRNA PIP5K1C GDSC1000 pan-cancer AAC -0.09 0.008
mRNA ZFP92 GDSC1000 pan-cancer AAC -0.091 0.008
mRNA PIGZ GDSC1000 pan-cancer AAC -0.092 0.008
mRNA HTRA2 GDSC1000 pan-cancer AAC -0.095 0.008
mRNA RBM5 GDSC1000 pan-cancer AAC -0.11 0.008
mRNA NUP160 GDSC1000 pan-cancer AAC 0.094 0.008
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