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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA IRF6 GDSC1000 pan-cancer AAC 0.11 0.02
mRNA GNMT GDSC1000 pan-cancer AAC -0.079 0.02
mRNA UVRAG GDSC1000 pan-cancer AAC -0.089 0.02
mRNA PHYHD1 GDSC1000 pan-cancer AAC -0.077 0.02
mRNA TSR2 GDSC1000 pan-cancer AAC -0.077 0.02
mRNA USP36 GDSC1000 pan-cancer AAC -0.078 0.02
mRNA GABRD GDSC1000 pan-cancer AAC -0.076 0.02
mRNA USP35 GDSC1000 pan-cancer AAC -0.075 0.02
mRNA C1QTNF6 GDSC1000 pan-cancer AAC 0.08 0.02
mRNA TCF15 GDSC1000 pan-cancer AAC -0.078 0.02
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