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XAV-939

XAV-939

Synonyms

Sources	Names Used
GDSC1000	XAV939
PharmacoGx	XAV-939

External IDs

Database	Identifier
Smiles:	C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey:	KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem:	2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to XAV-939

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PTCD3	GDSC1000	pan-cancer	AAC	-0.084	0.02
mRNA	VENTX	GDSC1000	pan-cancer	AAC	-0.079	0.02
mRNA	FAIM2	GDSC1000	pan-cancer	AAC	-0.086	0.02
mRNA	SCAF11	GDSC1000	pan-cancer	AAC	0.081	0.02
mRNA	MMD	GDSC1000	pan-cancer	AAC	0.084	0.02
mRNA	NACC2	GDSC1000	pan-cancer	AAC	0.078	0.02
mRNA	SMOC2	GDSC1000	pan-cancer	AAC	-0.078	0.02
mRNA	PITX1	GDSC1000	pan-cancer	AAC	0.086	0.02
mRNA	CDC27	GDSC1000	pan-cancer	AAC	0.081	0.02
mRNA	TAOK3	GDSC1000	pan-cancer	AAC	0.089	0.02

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