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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA KLF15 GDSC1000 pan-cancer AAC -0.087 0.02
mRNA SAT1 GDSC1000 pan-cancer AAC 0.09 0.02
mRNA OR2B11 GDSC1000 pan-cancer AAC 0.08 0.02
mRNA SSR1 GDSC1000 pan-cancer AAC -0.082 0.02
mRNA UTP14A GDSC1000 pan-cancer AAC -0.082 0.02
mRNA TNFAIP3 GDSC1000 pan-cancer AAC 0.09 0.02
mRNA NEDD9 GDSC1000 pan-cancer AAC 0.085 0.02
mRNA TLDC1 GDSC1000 pan-cancer AAC 0.099 0.02
mRNA ABHD11 GDSC1000 pan-cancer AAC -0.1 0.02
mRNA BNC1 GDSC1000 pan-cancer AAC 0.1 0.02
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