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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA NECAB3 GDSC1000 pan-cancer AAC -0.085 0.02
mRNA PCDHB16 GDSC1000 pan-cancer AAC -0.091 0.02
mRNA SPATA32 GDSC1000 pan-cancer AAC 0.08 0.02
mRNA MRFAP1L1 GDSC1000 pan-cancer AAC -0.082 0.02
mRNA GTF2F2 GDSC1000 pan-cancer AAC 0.084 0.02
mRNA GBP1 GDSC1000 pan-cancer AAC 0.089 0.02
mRNA BICC1 GDSC1000 pan-cancer AAC 0.11 0.02
mRNA C19orf45 GDSC1000 pan-cancer AAC -0.082 0.02
mRNA DDX60 GDSC1000 pan-cancer AAC 0.087 0.02
mRNA ZFPM1 GDSC1000 pan-cancer AAC -0.083 0.02
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