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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA ADCY3 GDSC1000 pan-cancer AAC -0.085 0.01
mRNA TEX264 GDSC1000 pan-cancer AAC -0.09 0.01
mRNA CCDC136 GDSC1000 pan-cancer AAC -0.094 0.01
mRNA HS1BP3 GDSC1000 pan-cancer AAC -0.09 0.01
mRNA WFDC13 GDSC1000 pan-cancer AAC 0.083 0.01
mRNA HMGN1 GDSC1000 pan-cancer AAC 0.091 0.01
mRNA CLDN1 GDSC1000 pan-cancer AAC 0.1 0.01
mRNA C15orf48 GDSC1000 pan-cancer AAC 0.097 0.01
mRNA S100A9 GDSC1000 pan-cancer AAC 0.091 0.01
mRNA ARID5A GDSC1000 pan-cancer AAC -0.1 0.01
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