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XAV-939

XAV-939

Synonyms

Sources	Names Used
GDSC1000	XAV939
PharmacoGx	XAV-939

External IDs

Database	Identifier
Smiles:	C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey:	KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem:	2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to XAV-939

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MLPH	GDSC1000	pan-cancer	AAC	0.069	0.08
mRNA	CXCL5	GDSC1000	pan-cancer	AAC	0.062	0.09
mRNA	AFTPH	GDSC1000	pan-cancer	AAC	-0.068	0.09
mRNA	C9orf66	GDSC1000	pan-cancer	AAC	-0.059	0.09
mRNA	DNAJC5B	GDSC1000	pan-cancer	AAC	-0.062	0.09
mRNA	KTN1	GDSC1000	pan-cancer	AAC	0.062	0.09
mRNA	HIP1	GDSC1000	pan-cancer	AAC	-0.059	0.09
mRNA	ACRBP	GDSC1000	pan-cancer	AAC	-0.062	0.09
mRNA	PSMB2	GDSC1000	pan-cancer	AAC	0.058	0.09
mRNA	CYTH4	GDSC1000	pan-cancer	AAC	-0.067	0.09

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