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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA CYP24A1 GDSC1000 pan-cancer AAC 0.13 0.0004
mRNA PLD5 GDSC1000 pan-cancer AAC 0.12 0.0004
mRNA TCTA GDSC1000 pan-cancer AAC -0.12 0.0005
mRNA TNFSF11 GDSC1000 pan-cancer AAC 0.12 0.0005
mRNA ZNF266 GDSC1000 pan-cancer AAC -0.13 0.0005
mRNA SCN5A GDSC1000 pan-cancer AAC -0.12 0.0005
mRNA TMOD3 GDSC1000 pan-cancer AAC 0.13 0.0005
mRNA PARP8 GDSC1000 pan-cancer AAC 0.13 0.0005
mRNA EFEMP1 GDSC1000 pan-cancer AAC 0.14 0.0005
mRNA C7orf57 GDSC1000 pan-cancer AAC 0.12 0.0006
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