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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA OR51I2 GDSC1000 pan-cancer AAC 0.089 0.009
mRNA CTAGE1 GDSC1000 pan-cancer AAC 0.087 0.009
mRNA MMAB GDSC1000 pan-cancer AAC -0.089 0.009
mRNA APBB1 GDSC1000 pan-cancer AAC -0.098 0.009
mRNA CTGF GDSC1000 pan-cancer AAC 0.11 0.009
mRNA RPL22 GDSC1000 pan-cancer AAC -0.092 0.009
mRNA ARIH2 GDSC1000 pan-cancer AAC -0.093 0.009
mRNA C10orf55 GDSC1000 pan-cancer AAC 0.088 0.009
mRNA RNF217 GDSC1000 pan-cancer AAC 0.1 0.009
mRNA STPG2 GDSC1000 pan-cancer AAC 0.088 0.01
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