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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF487 GDSC1000 pan-cancer AAC 0.083 0.02
mRNA QKI GDSC1000 pan-cancer AAC 0.096 0.02
mRNA SUSD1 GDSC1000 pan-cancer AAC 0.084 0.02
mRNA NRG2 GDSC1000 pan-cancer AAC -0.08 0.02
mRNA POPDC3 GDSC1000 pan-cancer AAC 0.091 0.02
mRNA USP43 GDSC1000 pan-cancer AAC 0.097 0.02
mRNA SMCO4 GDSC1000 pan-cancer AAC -0.086 0.02
mRNA BCOR GDSC1000 pan-cancer AAC -0.091 0.02
mRNA NTN4 GDSC1000 pan-cancer AAC 0.096 0.02
mRNA BST1 GDSC1000 pan-cancer AAC 0.08 0.02
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