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XAV-939

Synonyms

SourcesNames Used
GDSC1000XAV939
PharmacoGx XAV-939

External IDs

DatabaseIdentifier
Smiles: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
Inchikey: KLGQSVMIPOVQAX-UHFFFAOYSA-N
Pubchem: 2726824

Annotated Targets

TNKS, TNKS2

FDA Approval Status

Not Approved
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Top molecular features associated with response to XAV-939


Feature TypeStandardized
Nominal ANOVA
mRNA KIAA1257 GDSC1000 pan-cancer AAC -0.082 0.02
mRNA MAP3K3 GDSC1000 pan-cancer AAC -0.088 0.02
mRNA AVL9 GDSC1000 pan-cancer AAC 0.083 0.02
mRNA C20orf144 GDSC1000 pan-cancer AAC -0.083 0.02
mRNA CLCN6 GDSC1000 pan-cancer AAC -0.086 0.02
mRNA FOXRED2 GDSC1000 pan-cancer AAC -0.084 0.02
mRNA ROPN1L GDSC1000 pan-cancer AAC -0.079 0.02
mRNA COL4A6 GDSC1000 pan-cancer AAC 0.086 0.02
mRNA CLDN15 GDSC1000 pan-cancer AAC -0.09 0.02
mRNA SNX21 GDSC1000 pan-cancer AAC -0.088 0.02
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